Ascorbyl Tetraisopalmitate vs. Ascorbyl Palmitate: What's the Difference?

Ascorbyl Tetraisopalmitate vs. Ascorbyl Palmitate: What's the Difference?

When it comes to skincare ingredients that pack a real punch, Vitamin C is often at the top of the list. Renowned for its brightening and anti-aging properties, this powerhouse vitamin isn't just a one-trick pony. However, not all Vitamin C is created equal, and today we're diving into the specifics of two popular derivatives: Ascorbyl Tetraisopalmitate and Ascorbyl Palmitate. Let’s explore how these two stack up against each other and uncover which might just be the secret weapon your skincare routine is missing.

What Are Vitamin C Derivatives?

First off, why derivatives? Pure Vitamin C, known as ascorbic acid, is notoriously unstable when exposed to light and air, which complicates its use in skincare. To combat this, scientists have developed more stable forms of Vitamin C, which maintain their effectiveness longer and are often gentler on the skin.



Ascorbyl Tetraisopalmitate vs. Ascorbyl Palmitate

Both Ascorbyl Tetraisopalmitate and Ascorbyl Palmitate are modified versions of Vitamin C designed to offer increased stability and unique benefits. Here’s a breakdown of what makes each tick:

  • Ascorbyl Tetraisopalmitate: This oil-soluble form is celebrated for its ability to sink deep into the skin, where it goes to work boosting collagen production, fighting off radicals, and brightening your complexion. Its deep penetration capabilities mean it starts working faster and more effectively at lower concentrations.
  • Ascorbyl Palmitate: Although it's less potent than its counterpart, this derivative is also fat-soluble and provides excellent surface-level antioxidant protection. It's particularly good at fending off environmental pollutants and helping to rejuvenate the outermost layers of your skin.

Benefits Breakdown

Here's a closer look at the specific benefits each of these Vitamin C forms brings to the table:

Ascorbyl Tetraisopalmitate:

  • Boosts Collagen: Ideal for those looking to firm up their skin and reduce the appearance of fine lines.
  • Enhances Brightness: Works wonders in evening out skin tone and adding that sought-after glow.
  • Rapid Absorption: Because it’s oil-soluble, it absorbs without leaving a greasy residue, making it a favourite for those with deeper skincare goals.
Ascorbyl Palmitate:
  • Protects Against Damage: Offers a strong defence against pollution and UV rays, albeit more superficially.
  • Stabilizes Vitamin E: Helps to enhance the effects of Vitamin E in the skin, which is vital for repairing damaged skin cells.
  • Gentle on Skin: Its less intense nature makes it suitable for those with sensitive skin or those new to Vitamin C.

Comparative Analysis: At a Glance

Let's sum up the main points about these two derivatives in a simple, easy-to-read table:

Feature Ascorbyl Tetraisopalmitate Ascorbyl Palmitate
Stability High Moderate
Skin Penetration Deep Surface
Best For Anti-aging, brightening Environmental protection, mild use
Typical Use Concentration Lower Higher
Cost Higher Lower


Making the Right Choice

Choosing between Ascorbyl Tetraisopalmitate and Ascorbyl Palmitate depends largely on your skin's needs:

  • If deeper, more comprehensive skin rejuvenation is your goal, Ascorbyl Tetraisopalmitate might be the best choice. Its ability to work beneath the skin’s surface to promote collagen production and brighten skin tone is unmatched.
  • For those more concerned with daily environmental protection and have sensitive skin that reacts poorly to deeper penetrating acids, Ascorbyl Palmitate offers a gentler, albeit less potent, alternative.


While both Ascorbyl Tetraisopalmitate and Ascorbyl Palmitate offer fantastic benefits, Ascorbyl Tetraisopalmitate might just edge out its competition for those seeking deep, transformative results. Its ability to deliver potent benefits deep within the skin layers, combined with its superior stability and rapid absorption, makes it an exceptional choice for anyone serious about upgrading their skincare game. It's also the reason we use Ascorbyl Tetraisopalmitate in our best selling face serums and nourishing moisturisers.

Whether you're aiming to brighten, tighten, or simply protect your skin, incorporating a well-chosen Vitamin C serum can significantly enhance your skincare routine. As with any ingredient, listen to your skin, and don't be afraid to experiment to find what works best for you.

Reading next

Which Vitamin C serum is best?
Why Choose a Bakuchiol Serum in 2024?